Astrazeneca, Pfizer Vaccines Effective In High-Risk Groups

PHE, in a Friday research based on a pre-print survey of 1 million vulnerable people, reported that the vaccines used by Pfizer and AstraZeneca were effectiveness to fight symptomatic COVID-19 infection in high-risk groups.

In risk groups the overall efficacy of vaccines against symptomatic conditions was around 60 percent following a single dose either of AstraZeneca or Pfizer-BioNTech, PHE stated.

After a second dosage in persons in risk categories aged 16 to 64 years, this increases to 81% for AstraZeneca with no Pfizer data. Among those more than 64, 89 percent were successful and 80 percent were effective, claimed the health service. AstraZeneca was effective after the second dose.

"These real-world results demonstrate that most individuals who are clinically susceptible to COVID-19 are still highly protected after two doses of vaccination," said Mary Ramsay, Head of PHE Immunization.

Vaccine against AstraZeneca

The emergency vaccine has been listed for emergency use by WHO in two variants – manufactured by AstraZenecan-SKBio in Korea and by Serum Institute in India.

Data on the quality, safety, and effectiveness of the vaccine have been extensively evaluated by EMA and conditional marketing authorization is recommended for persons aged 18 years and older.

The WhO's World Consultative Committee on Vaccine Safety, an expert committee, is receiving reports on suspected safety incidents of potentially worldwide effect that give independent and authoritative advice to the WHO on safe vaccine use.

The COVID-19 vaccination for AZD1222 was 63.09% effective against SARS-CoV-2 symptomatic illness.

Increased dosage effectiveness is related with longer dose intervals between 8 to 12 weeks.

About on Pfizer Vaccine

What are the components of the COVID-19 vaccine of Pfizer-BioNTech?

MRNA, lipids, potassium chloride, potassium monobasic phosphate, sodium chloride, dibasic sodium phosphate dihydrate, and sucrose are the components.

How is a vaccination using mRNA working?

mRNA, sent by lipid nanoparticles to your organic cells, tells the cells to produce the spike protein that is present on the surface of the new coronavirus that triggers infection. The cells are instructed to create the spike protein and to produce antibodies specific to the spike SARS-CoV-2, which will stimulate an immunological response.

No viral particles are contained in mRNA vaccines, which indicate that the weakened or dead portions of viruses or bacteria are not contained in them.

Do mRNA vaccinations alter the DNA of a person?

MRNA is an information transitory transporter which doesn't fit with human DNA. MRNA does not enter the nucleus of a cell that holds our DNA.

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